Washington University School of Medicine

Translational Chemistry
& Drug Discovery

Bridging academic innovation with commercial impact through synthetic chemistry, high-throughput screening, and strategic industry partnerships.

Our Research Focus

Three Pillars of Discovery

Integrated expertise spanning synthetic methodology, chemical screening, and translational biology.

Small Molecule Synthesis

Development of novel Pd and Ni-catalyzed methodologies for allene synthesis, cross-coupling reactions, and asymmetric transformations.

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Drug Discovery & Screening

Medicinal chemistry programs targeting taccalonolide analogs for cancer treatment and high-throughput screening platforms for hit identification.

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Translational Biology

Collaborative programs bridging chemical discovery with disease biology, from target validation to preclinical development.

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Recent

2025: New publication in ACS Med. Chem. Lett. on [18F]-Taccalonolide pharmacokinetics

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Join Our Research Team

We are always looking for talented researchers, graduate students, and industry partners who share our passion for translational chemistry and drug discovery.